The serum ferritin levels by radioimmunoassay were measured in the subjects of normal, iron deficiency anemia and non-iron deficiency anemia and was compared with serum iron, total iron binding capacity and percentage saturation of transferrin.
The followings were obtained.
1. There were significant decrease in serum iron (62.7±24.4pg/dl, p<0.05) and sig￢nificant increase in total iron binding capacity(324.2±76.7kg/dl, pcontrast to normal control.
2. The serum ferritin levels were decreased significantly in iron deficiency anemia (13.9±10.7ng/ml, p<0.005) than normal control (82.5±48.Ong/ml). But serum ferritin levels in non-iron deficiency anemia showed wide variation (364.5±395.8ng/ml).
3. There was no significant correlation between serum iron, total iron binding capacity and serum ferritin in iron deficiency anemia, but serum ferritin was more significant in the diagnosis of iron deficiency anemia.
4. In non-iron deficiency anemia, there was no significant correlation and diagnostic significance hetween serum iron, total iron binding capacity and serum ferritin.
5. In iron deficiency anemia, the serum ferritin levels had no significant correlation with degree of anemia, but was tendency of correlation with percentage of transferrin iron saturation.
6. In liver diseases, blocd dyscrasias and typhoid fever, the serum ferritin revealed very high levels in spite of moderate to marked degree of anemia.
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